Neuromodulators: Whatโ€™s the Difference Between BOTOX, Dysport, Jeuveau, and Xeomin?

Mirror 3D Imaging
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Medically reviewed by
Dr. Jacob Sedgh, MD
Double Board-Certified Facial Plastic Surgeon

Dr. Sedgh is recognized for his skills in performing non-surgical enhancements in West Hollywood. He offers neuromodulator injections with BOTOX, Dysport, Jeuveau, and Xeomin to help his patients achieve a refreshed, more youthful facial look. Each one of these cosmetic injectables, all of which are derived from botulinum toxin, works to reduce laugh lines, fine lines, and wrinkles โ€“ but was developed with a slightly different formula. What are the differences between these injectables?

What are neuromodulators and what are they used for?

Neuromodulators have an active ingredient: botulinum toxin. This substance is injected into the muscle beneath the skin to relax the muscles that constantly contract, leading to fine lines, wrinkles, and crowโ€™s feet, leaving you appearing youthful and refreshed.

What is the difference between BOTOX, Jeuveau, Dysport, and Xeomin, and which is best for me?

The differences between BOTOX, Jeuveau, Dysport, and Xeomin are minor, but choosing the correct injectable requires a full understanding of how they function and choosing right for your skin condition. These non-surgical injections reduce fine lines, wrinkles, and smooth your skin for about four months following each treatment. All these products are formulated from the botulinum toxin but are produced differently. Xeomin, called the naked injectable, contains only botulinum toxin A without added proteins. BOTOX, Jeuveau, and Dysport have botulinum toxin A encased in proteins. Each has specific characteristics, and one may work better than another, based on how your body reacts to the injections.

BOTOX benefits

  • BOTOX is the most popular of all non-surgical injectable treatments.
  • It is frequently injected as a preventive measure to ward off wrinkle development.
  • BOTOX has other medical uses including treatment of migraines, certain eye disorders, sweating, and temporomandibular disorder (TMJ)
  • Botox is slightly less diluted than Dysport, meaning fewer units may be needed per treatment area. Itโ€™s versatile for small, precise zones such as the eyes or forehead creases, where controlled placement is key.

Jeuveau benefits

  • Jeuveau is the latest neuromodulator treatment to become available in the USA, manufactured with an advanced method for encasing the toxin in a protein structure.
  • Jeuveau had no serious side effects during clinical trials.

Dysport benefits

  • Dysport diffuses more than BOTOX, Jeuveau, and Xeomin due to the structure of its protein.
  • You can have fewer injections over a larger treatment area like the forehead and around the mouth.
  • Dysport lasts close to four months.
  • Dysport is especially effective for moderate to severe glabellar lines (the โ€œ11โ€ lines between the eyebrows). Itโ€™s known for providing smooth, natural movement rather than a frozen look.

Xeomin benefits

  • No additives in formulation โ€“ pure botulinum toxin A.
  • You may have better results if you have developed a resistance to the additives in the other formulas.
  • Xeomin diffuses into the tissues slightly differently, due to the lack of the proteins in the formula.
  • Xeomin is very effective in smoothing deeper frown lines between the brows.

Each of these neuromodulators is slightly different. Consulting with Dr. Sedgh can help you learn which treatment is right for you and produce the most natural, authentic smoothing effect.

What to Expect During Treatment

Neuromodulator injections are quick and virtually painless.

  • Duration: Treatments typically take 10โ€“20 minutes.
  • Comfort: No anesthesia is required, though topical numbing cream or ice may be applied.
  • Process: Using a fine needle, your provider injects precise amounts into targeted muscles to smooth wrinkles without affecting nearby areas.

Both Botox and Dysport treatments are often called โ€œlunchtime proceduresโ€ due to minimal downtime. Most patients resume daily activities immediately afterward.

Recovery and Results

You may experience slight redness, swelling, or tenderness at the injection sites, which subsides within hours.

Results Timeline:

  • Dysport: 2โ€“3 days
  • Botox, Jeuveau, Xeomin: 3โ€“7 days
  • Duration: 3โ€“4 months, varying slightly by patient metabolism and treatment area.

To maintain smooth, youthful results, repeat treatments are recommended two to three times per year.

Why should I choose Dr. Sedgh for injections?

Dr. Sedgh is a double board-certified facial plastic surgeon who has achieved acclaim for his ability to create natural-looking results, and he specializes in facial esthetics. This expertise makes him uniquely qualified to smooth wrinkles and crowโ€™s feet and produce a beautiful change. Dr. Sedghโ€™s skill with neuromodulator injections with BOTOX, Dysport, Xeomin, and Jeuveau can rejuvenate, refresh, and leave you appearing far younger.

If you want a fresh look that has an authentic appearance, not frozen or unnatural, Dr. Sedgh is the doctor to choose.ย  If you wish to learn more or schedule a consultation, don’t hesitate to contact us today.

Posted on behalf of Sedgh Plastic Surgery

COMFORT & TRANSPARENCY FROM START TO FINISH

When under our care, Dr. Sedgh always ensures you feel comfortable, cared for, well-informed about every aspect of your upcoming treatment, whether surgical or non-surgical. With an approach which focuses on achieving refreshed, natural-looking results, Dr. Sedgh prides himself on always acting with transparency, honesty, and the highest level of ethical treatment, from start to finish.